Paracetamol availability and overdose in Ireland.
نویسندگان
چکیده
New regulations for the control of paracetamol come into force in October 2001. These are greatly welcomed and should lead to a reduction in paracetamol poisoning. Existing conditions for the sale and supply of paracetamol (Irish Medicines Board (IMB), 1997), which have no statutory basis, state that non-pharmacy outlets should only sell emergency supplies of paracetamol in a maximum pack size of 12 tablets; just one pack should be sold on each occasion2. This study found that non-pharmacy outlets do not comply with these IMB conditions. Paracetamol poisoning remains the most common form of overdose requiring hospital admission in Ireland. Admissions increased by 29% between 1993 and 1999. The new regulations will give effect to the IMB conditions.
منابع مشابه
Ease of access is a principal factor in the frequency of paracetamol overdose.
BACKGROUND In Ireland, 30% of non-fatal overdoses involve paracetamol. AIMS To determine how and where patients obtained paracetamol, to assess awareness of toxicity and examine the relationship between dose and suicidal intent. METHODS A prospective study of patients admitted following a paracetamol overdose recording their reasons for using paracetamol, their knowledge of its toxicity and...
متن کاملParacetamol as a toxic substance for children: aspects of legislation in selected countries
Paracetamol is used widely in pediatrics because it has a high drug safety when used in therapeutic dosages. In case of overdose the majority of paracetamol is metabolized to N-acetyl-p-benzoquinone imine (NAPQI), which is responsible for the severe toxic effects. The covalent connection between NAPQI and hepatic proteins leads to hepatocellular damage and possibly to severe liver failure. The ...
متن کاملUse of paracetamol for suicide and non-fatal poisoning in the UK and France: are restrictions on availability justified?
OBJECTIVE To investigate the relationship between the availability of paracetamol and its use for overdose and suicide. DESIGN Analysis of routinely collected information on time trends for paracetamol suicides, non-fatal overdoses, and sales. SETTING England and Wales and France. RESULTS There were strong correlations between trends in paracetamol sales in the UK and trends in non-fatal ...
متن کاملUse of analgesics in intentional drug overdose presentations to hospital before and after the withdrawal of distalgesic from the Irish market
BACKGROUND Distalgesic, the prescription-only analgesic compound of paracetamol (325 mg) and dextropropoxyphene (32.5 mg) known as co-proxamol in the UK, was withdrawn from the Irish market as of January 2006. This study aimed to evaluate the impact of the withdrawal of distalgesic in terms of intentional drug overdose (IDO) presentations to hospital emergency departments (EDs) nationally. ME...
متن کاملImpact of different pack sizes of paracetamol in the United Kingdom and Ireland on intentional overdoses: a comparative study
BACKGROUND In order to reduce fatal self-poisoning legislation was introduced in the UK in 1998 to restrict pack sizes of paracetamol sold in pharmacies (maximum 32 tablets) and non-pharmacy outlets (maximum 16 tablets), and in Ireland in 2001, but with smaller maximum pack sizes (24 and 12 tablets). Our aim was to determine whether this resulted in smaller overdoses of paracetamol in Ireland c...
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ورودعنوان ژورنال:
- Irish medical journal
دوره 94 7 شماره
صفحات -
تاریخ انتشار 2001